Crimean–Congo hemorrhagic fever nosocomial infection in a immunosuppressed patient, Pakistan: Case report and virological investigation
Identifieur interne : 001B14 ( Main/Exploration ); précédent : 001B13; suivant : 001B15Crimean–Congo hemorrhagic fever nosocomial infection in a immunosuppressed patient, Pakistan: Case report and virological investigation
Auteurs : Zahra Hasan [Pakistan, États-Unis] ; Faisal Mahmood [Pakistan] ; Bushra Jamil [Pakistan] ; Barry Atkinson [Royaume-Uni] ; Murtaza Mohammed [Pakistan] ; Azra Samreen [Pakistan] ; Lamia Altaf [Pakistan] ; Tariq Moatter [Royaume-Uni] ; Roger Hewson [Royaume-Uni]Source :
- Journal of Medical Virology [ 0146-6615 ] ; 2013-03.
English descriptors
- Teeft :
- Alternative genogroups, Arab emirates, Baluchistan province, Calcineurin inhibitors, Case report, Cchf, Cchfv, Chronic liver disease, Dengue fever, Early diagnosis, Haemorrhagic fever, Hemorrhagic, Hemorrhagic fever, Hemorrhagic fever outbreak, Hemorrhagic fever virus, Likely multifactorial, Liver transplant, Liver transplant recipients, Maximum likelihood tree, Nosocomial, Nosocomial transmission, Phylogenetic, Rapid diagnosis, Risk assessment, Sequence alignment, Thrombotic microangiopathy, Transplant, University hospital, Viral, Viral hemorrhagic fever, Viral hemorrhagic fevers, Viral load, Virol, Wiley periodicals.
Abstract
Crimean–Congo hemorrhagic fever (CCHF) is endemic in the Baluchistan province, Pakistan. Sporadic outbreaks of CCHF occur throughout the year especially in individuals in contact with infected livestock. Nosocomial transmission remains a risk due to difficulties in the diagnosis of CCHF and limited availability of facilities for the isolation of suspected patients. Rapid diagnosis of CCHF virus infection is required for early management of the disease and to prevent transmission. This study describes the case of a 43‐year‐old surgeon who contracted CCHF during a surgical procedure in Quetta, Baluchistan and who was transferred to a tertiary care facility at the Aga Khan University Hospital, Karachi within 1 week of contracting the infection. Diagnosis of CCHF was made using a rapid real‐time reverse transcription polymerase chain reaction (RT‐PCR) assay for CCHF viral RNA. The patient had chronic hepatitis B and hepatitis D infection for which he had previously received a liver transplant. He proceeded to develop classic hemorrhagic manifestations and succumbed to the infection 14 days post‐onset of disease. There was no further nosocomial transmission of the CCHF during the hospital treatment of the surgeon. Early diagnosis of CCHF enables rapid engagement of appropriate isolation, barrier nursing and infection control measures thus preventing nosocomial transmission of the virus. J. Med. Virol. 85:501–504, 2013. © 2012 Wiley Periodicals, Inc.
Url:
DOI: 10.1002/jmv.23473
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001386
- to stream Istex, to step Curation: 001386
- to stream Istex, to step Checkpoint: 000392
- to stream Main, to step Merge: 001B24
- to stream Main, to step Curation: 001B14
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Crimean–Congo hemorrhagic fever nosocomial infection in a immunosuppressed patient, Pakistan: Case report and virological investigation</title><author><name sortKey="Hasan, Zahra" sort="Hasan, Zahra" uniqKey="Hasan Z" first="Zahra" last="Hasan">Zahra Hasan</name></author><author><name sortKey="Mahmood, Faisal" sort="Mahmood, Faisal" uniqKey="Mahmood F" first="Faisal" last="Mahmood">Faisal Mahmood</name></author><author><name sortKey="Jamil, Bushra" sort="Jamil, Bushra" uniqKey="Jamil B" first="Bushra" last="Jamil">Bushra Jamil</name></author><author><name sortKey="Atkinson, Barry" sort="Atkinson, Barry" uniqKey="Atkinson B" first="Barry" last="Atkinson">Barry Atkinson</name></author><author><name sortKey="Mohammed, Murtaza" sort="Mohammed, Murtaza" uniqKey="Mohammed M" first="Murtaza" last="Mohammed">Murtaza Mohammed</name></author><author><name sortKey="Samreen, Azra" sort="Samreen, Azra" uniqKey="Samreen A" first="Azra" last="Samreen">Azra Samreen</name></author><author><name sortKey="Altaf, Lamia" sort="Altaf, Lamia" uniqKey="Altaf L" first="Lamia" last="Altaf">Lamia Altaf</name></author><author><name sortKey="Moatter, Tariq" sort="Moatter, Tariq" uniqKey="Moatter T" first="Tariq" last="Moatter">Tariq Moatter</name></author><author><name sortKey="Hewson, Roger" sort="Hewson, Roger" uniqKey="Hewson R" first="Roger" last="Hewson">Roger Hewson</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:A13345A4808D9BC28E1A2A4D23D6E4737604CA6D</idno><date when="2013" year="2013">2013</date><idno type="doi">10.1002/jmv.23473</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-6HR08Z7J-S/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001386</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001386</idno><idno type="wicri:Area/Istex/Curation">001386</idno><idno type="wicri:Area/Istex/Checkpoint">000392</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000392</idno><idno type="wicri:doubleKey">0146-6615:2013:Hasan Z:crimean:congo:hemorrhagic</idno><idno type="wicri:Area/Main/Merge">001B24</idno><idno type="wicri:Area/Main/Curation">001B14</idno><idno type="wicri:Area/Main/Exploration">001B14</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Crimean–Congo hemorrhagic fever nosocomial infection in a immunosuppressed patient, Pakistan: Case report and virological investigation</title><author><name sortKey="Hasan, Zahra" sort="Hasan, Zahra" uniqKey="Hasan Z" first="Zahra" last="Hasan">Zahra Hasan</name><affiliation wicri:level="1"><country xml:lang="fr">Pakistan</country><wicri:regionArea>The Aga Khan University, Karachi</wicri:regionArea><wicri:noRegion>Karachi</wicri:noRegion></affiliation><affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country></affiliation><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">Pakistan</country><wicri:regionArea>Correspondence address: Associate Professor, Department of Pathology and Microbiology, The Aga Khan University, Stadium Road, Karachi 74800</wicri:regionArea><wicri:noRegion>Karachi 74800</wicri:noRegion></affiliation></author><author><name sortKey="Mahmood, Faisal" sort="Mahmood, Faisal" uniqKey="Mahmood F" first="Faisal" last="Mahmood">Faisal Mahmood</name><affiliation wicri:level="1"><country xml:lang="fr">Pakistan</country><wicri:regionArea>The Aga Khan University, Karachi</wicri:regionArea><wicri:noRegion>Karachi</wicri:noRegion></affiliation></author><author><name sortKey="Jamil, Bushra" sort="Jamil, Bushra" uniqKey="Jamil B" first="Bushra" last="Jamil">Bushra Jamil</name><affiliation wicri:level="1"><country xml:lang="fr">Pakistan</country><wicri:regionArea>The Aga Khan University, Karachi</wicri:regionArea><wicri:noRegion>Karachi</wicri:noRegion></affiliation></author><author><name sortKey="Atkinson, Barry" sort="Atkinson, Barry" uniqKey="Atkinson B" first="Barry" last="Atkinson">Barry Atkinson</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health Protection Agency, Porton Down, Salisbury</wicri:regionArea><wicri:noRegion>Salisbury</wicri:noRegion></affiliation></author><author><name sortKey="Mohammed, Murtaza" sort="Mohammed, Murtaza" uniqKey="Mohammed M" first="Murtaza" last="Mohammed">Murtaza Mohammed</name><affiliation wicri:level="1"><country xml:lang="fr">Pakistan</country><wicri:regionArea>The Aga Khan University, Karachi</wicri:regionArea><wicri:noRegion>Karachi</wicri:noRegion></affiliation></author><author><name sortKey="Samreen, Azra" sort="Samreen, Azra" uniqKey="Samreen A" first="Azra" last="Samreen">Azra Samreen</name><affiliation wicri:level="1"><country xml:lang="fr">Pakistan</country><wicri:regionArea>The Aga Khan University, Karachi</wicri:regionArea><wicri:noRegion>Karachi</wicri:noRegion></affiliation></author><author><name sortKey="Altaf, Lamia" sort="Altaf, Lamia" uniqKey="Altaf L" first="Lamia" last="Altaf">Lamia Altaf</name><affiliation wicri:level="1"><country xml:lang="fr">Pakistan</country><wicri:regionArea>The Aga Khan University, Karachi</wicri:regionArea><wicri:noRegion>Karachi</wicri:noRegion></affiliation></author><author><name sortKey="Moatter, Tariq" sort="Moatter, Tariq" uniqKey="Moatter T" first="Tariq" last="Moatter">Tariq Moatter</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health Protection Agency, Porton Down, Salisbury</wicri:regionArea><wicri:noRegion>Salisbury</wicri:noRegion></affiliation></author><author><name sortKey="Hewson, Roger" sort="Hewson, Roger" uniqKey="Hewson R" first="Roger" last="Hewson">Roger Hewson</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health Protection Agency, Porton Down, Salisbury</wicri:regionArea><wicri:noRegion>Salisbury</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Medical Virology</title><title level="j" type="alt">JOURNAL OF MEDICAL VIROLOGY</title><idno type="ISSN">0146-6615</idno><idno type="eISSN">1096-9071</idno><imprint><biblScope unit="vol">85</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="501">501</biblScope><biblScope unit="page" to="504">504</biblScope><biblScope unit="page-count">4</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2013-03">2013-03</date></imprint><idno type="ISSN">0146-6615</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0146-6615</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Alternative genogroups</term><term>Arab emirates</term><term>Baluchistan province</term><term>Calcineurin inhibitors</term><term>Case report</term><term>Cchf</term><term>Cchfv</term><term>Chronic liver disease</term><term>Dengue fever</term><term>Early diagnosis</term><term>Haemorrhagic fever</term><term>Hemorrhagic</term><term>Hemorrhagic fever</term><term>Hemorrhagic fever outbreak</term><term>Hemorrhagic fever virus</term><term>Likely multifactorial</term><term>Liver transplant</term><term>Liver transplant recipients</term><term>Maximum likelihood tree</term><term>Nosocomial</term><term>Nosocomial transmission</term><term>Phylogenetic</term><term>Rapid diagnosis</term><term>Risk assessment</term><term>Sequence alignment</term><term>Thrombotic microangiopathy</term><term>Transplant</term><term>University hospital</term><term>Viral</term><term>Viral hemorrhagic fever</term><term>Viral hemorrhagic fevers</term><term>Viral load</term><term>Virol</term><term>Wiley periodicals</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Crimean–Congo hemorrhagic fever (CCHF) is endemic in the Baluchistan province, Pakistan. Sporadic outbreaks of CCHF occur throughout the year especially in individuals in contact with infected livestock. Nosocomial transmission remains a risk due to difficulties in the diagnosis of CCHF and limited availability of facilities for the isolation of suspected patients. Rapid diagnosis of CCHF virus infection is required for early management of the disease and to prevent transmission. This study describes the case of a 43‐year‐old surgeon who contracted CCHF during a surgical procedure in Quetta, Baluchistan and who was transferred to a tertiary care facility at the Aga Khan University Hospital, Karachi within 1 week of contracting the infection. Diagnosis of CCHF was made using a rapid real‐time reverse transcription polymerase chain reaction (RT‐PCR) assay for CCHF viral RNA. The patient had chronic hepatitis B and hepatitis D infection for which he had previously received a liver transplant. He proceeded to develop classic hemorrhagic manifestations and succumbed to the infection 14 days post‐onset of disease. There was no further nosocomial transmission of the CCHF during the hospital treatment of the surgeon. Early diagnosis of CCHF enables rapid engagement of appropriate isolation, barrier nursing and infection control measures thus preventing nosocomial transmission of the virus. J. Med. Virol. 85:501–504, 2013. © 2012 Wiley Periodicals, Inc.</div></front></TEI><affiliations><list><country><li>Pakistan</li><li>Royaume-Uni</li><li>États-Unis</li></country></list><tree><country name="Pakistan"><noRegion><name sortKey="Hasan, Zahra" sort="Hasan, Zahra" uniqKey="Hasan Z" first="Zahra" last="Hasan">Zahra Hasan</name></noRegion><name sortKey="Altaf, Lamia" sort="Altaf, Lamia" uniqKey="Altaf L" first="Lamia" last="Altaf">Lamia Altaf</name><name sortKey="Hasan, Zahra" sort="Hasan, Zahra" uniqKey="Hasan Z" first="Zahra" last="Hasan">Zahra Hasan</name><name sortKey="Jamil, Bushra" sort="Jamil, Bushra" uniqKey="Jamil B" first="Bushra" last="Jamil">Bushra Jamil</name><name sortKey="Mahmood, Faisal" sort="Mahmood, Faisal" uniqKey="Mahmood F" first="Faisal" last="Mahmood">Faisal Mahmood</name><name sortKey="Mohammed, Murtaza" sort="Mohammed, Murtaza" uniqKey="Mohammed M" first="Murtaza" last="Mohammed">Murtaza Mohammed</name><name sortKey="Samreen, Azra" sort="Samreen, Azra" uniqKey="Samreen A" first="Azra" last="Samreen">Azra Samreen</name></country><country name="États-Unis"><noRegion><name sortKey="Hasan, Zahra" sort="Hasan, Zahra" uniqKey="Hasan Z" first="Zahra" last="Hasan">Zahra Hasan</name></noRegion></country><country name="Royaume-Uni"><noRegion><name sortKey="Atkinson, Barry" sort="Atkinson, Barry" uniqKey="Atkinson B" first="Barry" last="Atkinson">Barry Atkinson</name></noRegion><name sortKey="Hewson, Roger" sort="Hewson, Roger" uniqKey="Hewson R" first="Roger" last="Hewson">Roger Hewson</name><name sortKey="Moatter, Tariq" sort="Moatter, Tariq" uniqKey="Moatter T" first="Tariq" last="Moatter">Tariq Moatter</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001B14 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001B14 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:A13345A4808D9BC28E1A2A4D23D6E4737604CA6D
|texte= Crimean–Congo hemorrhagic fever nosocomial infection in a immunosuppressed patient, Pakistan: Case report and virological investigation
}}
| This area was generated with Dilib version V0.6.33. |  |